Detecting Cross-Linked Peptides by Searching against a Database of Cross-Linked Peptide Pairs
نویسندگان
چکیده
منابع مشابه
Detecting cross-linked peptides by searching against a database of cross-linked peptide pairs.
Mass spectrometric identification of cross-linked peptides can provide valuable information about the structure of protein complexes. We describe a straightforward database search scheme that identifies and assigns statistical confidence estimates to spectra from cross-linked peptides. The method is well suited to targeted analysis of a single protein complex, without requiring an isotope label...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2010
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr901163d